Senior Manufacturing Engineer

Posted 6/17/2026 · last confirmed live 8/26/2026

Rapidly Growing Life Sciences Technology Company Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.  We are looking for a highly motivated Senior Manufacturing Engineer to join our team! As a Senior Manufacturing Engineer, you will play an important role in the development and commercialization of technology and products that will accelerate our understanding of life, biology and disease and transform large industries. You will work as a part of Manufacturing Engineering Team supporting production on preparing, installing and configuring a variety of subassembly and system level components. This is a full-time onsite position at our Fremont, CA location. How You’ll Contribute  Responsible for all aspects of production documentation for complex DNA sequencing systems and sub-assemblies including Incoming Quality Control (IQC), build, test, and rework procedures Review, create, and update documentation for high volume procurement such as drawings for cables, Printed Circuit Board Assemblies (PCBA), electromechanical assemblies, and Off-The-Shelf (OTS) parts and subsystems Provide vendor feedback and review as needed to maintain incoming product quality and compliance Support new product development, engineering test, manufacturing test, and manufacturing and contract manufacturing (CM) outsourcing Work closely with R&D teams on design transfer, Engineering Change Order (ECO) implementation and Common Industrial Protocol (CIP) Facilitate and participate in feasibility studies alongside development engineering to build the product validation and test requirements/equipment to support manufacturing Be "first line of defense” for manufacturing issues and escalate through appropriate chains of communication to address them in a timely fashion Troubleshoot and conduct root cause analysis of production equipment and failed Operational Qualification (OQ) for electrical and electromechanical assemblies, and PCBAs Own continuous improvement of existing products to end of product life cycle Follow closely and manage the steps from development to full production; calling for a design freeze, pre-production test and validation builds (pilot builds), lead cross-functional communication between development, procurement, manufacturing, quality, and field operations Develop and maintain project schedules for design freezes for Bill of Materials (BOM) release, long lead time orders and risk buys Review designs to identify opportunities for improvement prior to release to production Maintain visibility and coordination of components for field testing Support quality in First Article Inspection (FAI) Apply Design for Manufacturability (DFM); Design for Assembly (DFA); and Design for Quality (DFQ) principles to optimize design and production Plan and execute change control implementation Understanding of test fixtures and system level integration, including Off-The-Shelf Input/Output OTS I/O vs in-house I/O, interfacing with firmware, software, and scripting; ability to set clear and qualified configurations for fixture and tool stability Other duties as assigned Qualifications, Skills, Knowledge & Abilities BS in Electrical Engineering, Manufacturing Engineering, Mechatronics, or a related field 5+ years of experience taking products from an R&D environment to full scale capital equipment production in the 10’s to 100’s and beyond Demonstrated experience working in a manufacturing environment building, testing, or troubleshooting automated instruments or robotic systems involving electrical and electro-mechanical assemblies, with a working understanding of their firmware and software-level control interfaces Proficiency in reading and interpreting PCB schematics, board layout, harness drawings, and multi-level BOMs to support build, inspection, and incoming quality review of electrical assemblies Hands-on experience using oscilloscopes, digital multimeters (DMMs), and other bench test equipment to diagnose quality or manufacturing defects at the board, harness, and system level Experience working as an Original Equipment Manufacturer (OEM) design owner Excellent technical writing skills to generate clear, precise documentation such as manufacturing instruction, rework, and deviation documents Strong understanding of manufacturing processes, New Product Introduction (NPI) activities, and product development lifecycle Product Lifecycle Management (PLM) experience with Arena or equivalent for multi-level nested BOMs and part management of assemblies up to several thousand-line items Experience with electrical CAD packages such as Altium, or KiCAD for PCB design and the ability to read schematics and understand board layout Experience with manufacturing and design of PCBAs, knowledge of In Process Control (IPC) standards, ISO 13485 or 9001, and familiarity with vendor management is a plus Automation and data analysis using Python is a plus Self-starter with a can-do attitude At Ultima Genomics, your base pay is one part of your total compensation package. This role pays between $110,000 and $130,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location.  Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits.  This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits. #LI-Onsite Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics’ EEO Policy and Know Your Rights . If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com .

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