Senior Director, US Medical Lead LC-FAOD and MPSs

Ultragenyx Pharmaceutical · United States - Remote · Remote

Posted 8/18/2026 · last confirmed live 8/26/2026

Apply on Ultragenyx Pharmaceutical’s site

Why Join Us?   Be a hero for our rare disease patients   At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.    Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.   If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team . Position Summary: ultra impact – Make a difference for those who need it most Ultragenyx is seeking an accomplished medical affairs leader, motivated by working in a   highly scientific,  innovative ,  and fast-paced environment, and driven to lead the future of rare disease medicine. This exceptional leader must have deep scientific  knowledge , strong business acumen ,  and exemplary communication skills. The  Senior Director  will play a key medical leadership role in the LC - FAOD and MPS franchise s  for the US region ,  supporting  assets with distinct lifecycle management cycle s . Work Model:  Remote: Officially documented as working full-time from home, with travel to Ultragenyx's offices or other locations on occasion as needed. Responsibilities: Serve as the medical lead for LC-FAOD, MPS VII and MPS IIIA, accountable for the regional pull-through of the global medical strategy, and the development and timely execution of US tactical plans aligned to brand strategy and lifecycle priorities   Serve as the UX111 US medical launch team, accountable for developing and leading the execution of a robust medical launch plan, partnering closely with the Field Medical and Gene Therapy Treatment Teams.  Provide clear directions to teams to ensure successful execution of the launch plan   Accountable to define and deliver meaningful strategic goals that demonstrate measurable impact on medical affairs and business outcomes   Lead and/or implement US data generation activities aligned to the integrated evidence plan / US m edical needs  and provide medical leadership  for  associated  evidence dissemination  activitie s   Build and maintain strong relationships with key opinion leaders (KOLs); integrate insights into strategic planning and lead collaborations on priority initiatives, such as advisory boards, QTC connect meetings and payer education as needed   Provide deep disease area and product  expertise , ensuring  accurate  and consistent communication of clinical and scientific data   Lead US conference strategy , including the  delivery of scientific  education  symposia and other educational events that  advance HCP knowledge and understanding of assigned programs   Collaborate closely with the US field medical team, supporting the full cycle of strategic insights generation through to action   Ensure development of impactful scientific resources (slide decks, FAQs, educational materials) for use by US field teams   Represent US medical and serve as an active contributor to the Global Medical Strategy Team on all assigned programs, ensuring that US insights inform global strategy   Provide medical and scientific  expertise  for  promotional and non-promotional  material s /medical affairs review committees, ensuring scientific accuracy, strategic alignment ,  suitability for use  and  compliant  with US regulations   Collaborate effectively with the Global Medical team and other cross-functional partners, including all commercialization functions, patient advocacy, clinical development, HEOR, diagnostics, scientific  communications  and publications  and  regulatory Requirements: MD with specialty training in metabolic genetics, with rare disease expertise, or PhD with substantial, relevant experience in the LC-FAOD and MPSs    At least five years’ experience in pharmaceutical/biotechnology industry, including US medical affairs   Demonstrated ability to develop and execute medical launch strategies in the US market is highly preferred   Proven leadership skills, including ability to navigate ambiguous situations and collaborate with cross functional teams on complex initiatives to drive alignment and decision-making   High aptitude for attention to detail, commitment to high-quality work, and sense of passion and urgency to achieve goals and improve the lives of patients   Proven ability to take initiative and drive successful execution of complex projects   Highly analytical and strategic thinker with the ability to identify interdependencies, consider medical implications, and understand broader program and organizational goals   Excellent communication skills, with the ability to articulate scientific and strategic concepts in both written documents and verbal presentations   Proactive, highly organized and manages shifting priorities in rapidly changing environment   Willingness and ability to travel up to 15% of the time   #LI-CS1  #LI-Remote The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location. This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment. Pay Range $270,500 — $334,100 USD   Full Time employees across the globe enjoy a range of benefits, including, but not limited to:   ·         Generous vacation time and public holidays observed by the company ·         Volunteer days ·         Long term incentive and Employee stock purchase plans or equivalent offerings ·         Employee wellbeing benefits ·         Fitness reimbursement ·         Tuition sponsoring ·         Professional development plans   * Benefits vary by region and country Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com . See our  CCPA Employee and Applicant Privacy Notice . See our  Privacy Policy . It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Note to External Recruiters : All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation.  Inquiries on developing a recruiting relationship with us, may be directed to :  talentacquisition@ultragenyx.com .

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