Senior Project Manager

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company · Boston, MA

Posted 7/17/2026 · last confirmed live 8/26/2026

Apply on Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company’s site

Description of Role Centessa is seeking a Senior Project Manager, that will leverage his/her project management and drug development experience to support one or more high complexity global R&D programs. This position will report to a Director, Project Management (Dir, PM).  Key Responsibilities Partner with the GTL (Global Team Leader) and Dir, PM to support the cross-functional matrix team, and project manage select sub-teams  Support the development of and continuously maintain assigned parts of detailed and fully cross-functionally integrated program Gantt chart as a company-wide “Single Source of Truth,” incorporating all relevant dependencies, and provide fit-for-purpose summary views for team use and executive management reviews Identify and manage interdependencies, critical path and at-risk activities to support program level scenario planning and risk management strategies Maintain relevant dashboards to communicate status and track progress  Manage cross-functional team meetings including scheduling, preparing agendas, presentation materials, and minutes that ensure proper follow up of action items Maintain issue logs and risks registers, and ensure team proactively resolve issues in a timely manner and that risks are mitigated as appropriate Work with cross-functional team and Finance to develop and update budgets, and manage program spend within approved budget 'Manage select external vendors (timelines, budgets, MSA/SOW documents, etc.) and integrate deliverables into program Gantt Support development of Governance and Executive presentations Provide support for the planning and preparation of documents to a quality standard required for Regulatory/Health Authority submissions Contribute to establishment and refinement of best practices, processes and procedures  Qualifications BS plus 5+ years experience in pharmaceutical/biotech R&D environment, including 3+ years as PM or equivalent Proven expertise in drug development and registration, including early and late-stage clinical, nonclinical, CMC development, and regulatory interactions, submissions/reviews globally Highly motivated, proactive, detail-oriented and organized self-starter with strong communication, collaboration, interpersonal skills, and influence to accomplish work without formal authority and to ensure optimal team performance Excellent analytical skills and expert in facilitating team decision making; competent in the application of decision analysis methodologies and related tools Expert knowledge of project management principles and practices with the ability to thrive in a fast-paced dynamic environment (PMP certification is highly desired), and expert in project management software, e.g., Smartsheet  Compensation The annual base salary range for this position is $185,000.00 to $200,000.00. Individual compensation within this range will be determined based on a variety of factors, including geographic location, qualifications, skills, relevant experience, job knowledge and location. In addition to base pay, this role is eligible for a discretionary annual bonus. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. Work Location The Senior Project Manager role is a based in the US, with occasional travel. POSITION:  Full-Time, Exempt EEOC Statement: Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.

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