Senior Manager, Accounting & FP&A

Posted 8/7/2026 · last confirmed live 8/26/2026

Location: Hammersmith Reporting to: Associate Director, Finance Job Summary Orchard Therapeutics is a global biotechnology gene therapy company dedicated to transforming the lives of people affected by rare diseases through the development of innovative, potentially curative cell and gene therapies. Orchard has its global headquarters in London and is a wholly owned subsidiary of Kyowa Kirin, a Japan-based Global Specialty Pharmaceutical Company. The Senior Manager, Accounting & FP&A will be a key member of the Finance team and will play a key role in financial reporting, month-end closing, and business partnering across G&A functions. The position requires an in-depth knowledge of accounting, internal controls, and experience of both internal and external financial planning, analysis and reporting. Success in this role will require the ability to work in a collaborative manner with peers, auditors and strategic partners, and to effectively communicate with various levels of management and external service providers. The ideal candidate will be a critical thinker and a proactive problem-solver with a collaborative mindset and a continuous improvement focus. Key Elements and Responsibilities · Manage general ledger accounts for G&A departments (HR, Legal, Facilities, IT, etc.) ensuring accurate and timely financial month-end close, including recording journal entries, reviewing account reconciliations and roll-forwards, and performing detailed account analyses. · Partner with G&A department leaders to deliver monthly financial reporting and support financial planning, budgeting and forecasting processes. · Prepare monthly, quarterly, and year-end financial reports. · Supervise and approve cash disbursements to third-party vendors, ensuring compliance with company policies and internal controls. · Partner with the payroll department to ensure accurate and timely recording of payroll-related journal entries and reconciliation of payroll accounts, including wages, taxes, benefits, and related accruals. · Assist in the preparation of monthly financial reporting to parent company. · Support internal and external audit processes, including documentation and response to inquiries. · Ensure compliance with accounting standards and internal accounting policies. · Drive process improvements and promote a culture of accuracy, accountability, and continuous improvement. Requirements Experience, Skills & Knowledge · 5+ years of progressive accounting experience, including hands-on operational roles within industry; experience in the pharmaceutical or biotech sector is preferred. · Strong knowledge of accounting principles, financial reporting and internal controls. · Strong proficiency in accounting systems; ideally with NetSuite, Adaptive Planning, and Concur · Advanced Excel skills are required, including proficiency with lookup functions, PivotTables, and handling large data sets. · The ability to communicate effectively through the use of different means to a broad range of individuals at all levels. · Highly organized with a high level of attention to detail and the ability to successfully manage competing priorities and meet internal and external deadlines to the desired standard. · A motivated self-starter that is quick to learn and, takes responsibility for day-to-day activities with minimal input and direction. · Analytical and proactive with a problem-solving mindset and focus on continuous improvement. · Professional, hard-working team player with a can-do attitude that acts responsibly in an ethical manner Education Bachelor’s degree in Accounting, Finance, or a related field. CA or CPA preferred

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