Director, Medical Affairs Strategy

Nuvalent, Inc. · Cambridge · Remote

Posted 8/5/2026 · last confirmed live 8/26/2026

The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer.  Nuvalent is an exciting company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.  The Role: Reporting to the Senior Director of Medical Affairs, the Director, Medical Strategy will support the development and execution of Medical Affairs strategy. This role will contribute to cross-functional planning and implementation of medical initiatives, including advisory boards, evidence generation, investigator-sponsored research (ISR), and promotional/medical material review. The Associate Director will collaborate closely with Clinical Development, Commercial, Regulatory, and Field Medical teams to ensure strategic alignment and seamless execution. Responsibilities: •    Support development and execution of annual Medical Affairs strategic and tactical plans. •    Collaborate cross-functionally with Clinical, Commercial, Regulatory, and Field Medical to ensure alignment with scientific and business objectives. •    Operationalize and manage Medical Affairs activities such as advisory boards, symposia, scientific congress planning, and educational initiatives. •    Serve as a key Medical Affairs contributor on the Promotional Review Committee (PRC) and Medical Review Committee (MRC) to ensure scientific accuracy, compliance, and alignment with medical strategy. •    Support the planning and implementation of the Investigator-Sponsored Research (ISR) program, including proposal review, coordination of internal evaluations, and communication with investigators. •    Partner with Clinical Development to integrate healthcare provider insights and support the design and execution of clinical trials. •    Collaborate with Commercial colleagues on compliant alignment of strategy and assist with development of promotional materials including slide decks, FAQs, and internal training content. •    Help develop and maintain internal Medical Affairs processes, SOPs, and guidance documents. •    Gather, synthesize, and share scientific and clinical insights from KOL interactions, advisory boards, and scientific conferences. •    Assist in vendor oversight and budget management for assigned initiatives. Competencies Include: •    Demonstrated ability to collaborate across matrixed, cross-functional teams in a fast-paced environment. •    Proven ability to manage multiple projects simultaneously with attention to timelines and detail. •    Strong communication and interpersonal skills; build trust and foster relationships internally and externally. •    Able to work independently, take initiative, and adapt quickly to evolving priorities. •    Recognized leader who exhibits effective communication, emotional intelligence, and influencing skills, within a matrix operating environment. •    Demonstration of strategic thinking and high-level planning while also balancing the ability to manage and execute operational details. •    Ability to effectively manage multiple projects with competing priorities. Qualifications:  •    Advanced, medical/scientific doctoral-level degree required: PharmD, PhD, MD (or equivalent). •    10 + years of experience in the pharmaceutical biotech or other relevant industries, including 3+ years in Medical Affairs is preferred •    Experience contributing to medical strategy with strong operational and executional skills. •    Oncology experience required; solid tumor experience strongly preferred. •    Prior experience supporting advisory boards, PRC/MRC, and ISR programs. •    Experience collaborating across Clinical and Commercial functions. •    Strong project management and scientific communication skills. •    Up to 25% domestic (and possibly international) travel Annual Salary Range $230,000 — $260,000 USD   Additional Information: Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages. The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “ no-reply@greenhouse.io ” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

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