Senior Regional Business Director (US Sales): Southeast

Posted 7/31/2026 · last confirmed live 8/26/2026

The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer.  Nuvalent is an exciting company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.  *This region will cover nine (9) states: Delaware, Georgia, Florida, Maryland, North & South Carolina, Alabama, Mississippi, and Virginia. *The candidate must live in the Region above. The Role: Reporting to the Vice President, US Sales, the Senior Regional Business Director will lead a high-performing field sales team in preparation for our first commercial launch. This individual will be responsible for executing Nuvalent’s sales strategy, driving market development, and ensuring the successful uptake of our targeted therapies within the oncology space. The Regional Business Director will play a critical role in building and coaching a best-in-class sales team, fostering strong relationships with key healthcare providers, and collaborating cross-functionally to optimize commercial success. Responsibilities: Build, lead, and develop a high-performing oncology sales team, ensuring strong clinical acumen and execution of Nuvalent’s go-to-market strategy. Drive sales performance and market penetration, ensuring that the team meets or exceeds sales goals within the assigned region. Develop and execute regional business plans, leveraging market insights, competitive intelligence, and customer feedback to optimize engagement strategies. Coach and mentor sales representatives to enhance their ability to effectively engage with oncologists and other key stakeholders. Foster a culture of accountability, collaboration, and performance, ensuring alignment with Nuvalent’s commercial objectives. Build strong relationships with key accounts, KOLs, and oncology centers, establishing Nuvalent as a trusted partner in patient care. Collaborate cross-functionally with Marketing, Medical Affairs, and Market Access to ensure seamless execution of commercial initiatives. Leverage digital CRM tools and omnichannel engagement strategies to track customer interactions, optimize outreach, and enhance field execution. Monitor and analyze sales data, market trends, and competitive dynamics, providing strategic recommendations to senior leadership. Ensure compliance with all regulatory and legal guidelines, upholding Nuvalent’s commitment to ethical business practices. Competencies Include: Sales Leadership & Team Development: Proven ability to build, develop, and lead a high-performing oncology sales team. Strategic Market Execution: Strong ability to develop and execute regional business plans that drive growth and competitive differentiation. Oncology & Clinical Acumen: Deep understanding of the oncology treatment landscape, HCP engagement strategies, and evolving market dynamics. Data-Driven Decision Making: Strong analytical skills to assess sales performance and market trends, driving informed business decisions. Cross-Functional Collaboration: Ability to work effectively with internal stakeholders to align sales efforts with broader commercial strategies. Customer Engagement Excellence: Skilled in developing relationships with oncologists, academic institutions, and community practices to drive brand adoption. Proficiency in digital CRM and omnichannel engagement: Ability to leverage digital tools, analytics platforms, and omnichannel strategies to optimize field sales execution and customer engagement.   Qualifications: Bachelor’s degree required; MBA or advanced degree preferred. 12+ years of biopharma experience, with at least 5+ years in oncology sales leadership. Successful track record of launching and commercializing oncology therapeutics in a competitive market. Proven ability to lead and coach high-performing sales teams in a fast-paced, result-driven environment. Strong understanding of the oncology marketplace, NSCLC treatment landscape, and targeted therapies preferred. Ability to travel up to 60% for field-based coaching, customer engagement, and regional/national meetings. Annual Salary Range $245,000 — $275,000 USD   Additional Information: Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages. The targeted salary range reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “ no-reply@greenhouse.io ” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

This role is published by Nuvalent, Inc. on greenhouse. SwiftFit is not the employer and does not accept applications.